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Pharmaceutical Science & Technology
Reviews “An in-depth discussion of coumarin research, encompassing issues such as extraction procedures, physicochemical features, targeted drug delivery systems, and clinical studies. . . . Delivers a thorough understanding of the principles that underpin coumarin anticancer properties and their prospective clinical uses. It discusses prodrug design strategies, nanoformulations, target-based derivatives, and coumarin-specific applications in diverse cancer types. Coumarin mechanisms of anticancer action are also investigated, offering information on their potential as enzyme inhibitors, radiosensitizers, and medicines targeting pathways involved in cancer growth. The book highlights the current state of coumarin research while also highlighting future directions and potential for cancer therapeutic innovation.” —From the Foreword by Prabhat Kumar Singh, Vice Chancellor, Uttar Pradesh University of Medical Sciences, India Coumarin, a naturally occurring benzo-á-pyrone compound that is most often used as a fragrance ingredient, is also beneficial in the treatment of prostate cancer, renal cell carcinoma, leukemia, and other cancers. This new volume provides an in-depth discussion of the various applications of coumarin compounds in cancer treatment, exploring the most recent developments, extraction processes, and tailored approaches to use coumarins for cancer treatment. It presents a complete overview of the distinct uses of coumarin compounds in cancer treatment as well as insights into their various modes of action and therapeutic efficacy. The book also addresses coumarin potential as an enzyme inhibitor for cancer management, the therapeutic potential of natural coumarin lead compounds, and the use of coumarin derivatives as radiosensitizers in cancer treatment. CONTENTS: About the Authors / Editors: Editors: Rishabha Malviya, PhD Professor, Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, India Rishabha Malviya, PhD, has 15 years of research experience and has been working as a Professor in the Department of Pharmacy, School of Medical and Allied Sciences at Galgotias University, India, for the past 11 years. His area of interest includes formulation optimization, nanoformulation, targeted drug delivery, localized drug delivery, and characterization of natural polymers as pharmaceutical excipients. He has authored more than 200 research/review papers for national/international journals of repute. He has 58 patents (19 grants, 38 published, one filed) and publications in reputed national and international journals with more than 450 cumulative impact factor. He has received an outstanding reviewer award from Elsevier. He has authored and/or edited 120 books (Wiley, Springer Nature, De Gruyter, CRC Press/Taylor and Francis, River Publisher, Apple Academic Press, Nova Science Publishers, and OMICS International) and authored 81 book chapters. His name has been included in the world’s top 2% scientist list for the years 2020–2025 by Elsevier BV and Stanford University. He is a reviewer, editor, and editorial board member of more than 50 national and international journals of repute. He completed a BPharm from Uttar Pradesh Technical University and an MPharm (Pharmaceutics) from Gautam Buddha Technical University, Lucknow Uttar Pradesh, India. His PhD (Pharmacy) work was in novel formulation development techniques. He has been invited as an author for Atlas of Science and for the pharma magazine dealing with industry (B2B), Ingredient South Asia Magazine. Kamla Pathak, PhD Dean and Professor, Faculty of Pharmacy, Uttar Pradesh University of Medical Sciences, Etawah, India Kamla Pathak, PhD, is Dean and Professor, Faculty of Pharmacy, Uttar Pradesh University of Medical Sciences, Etawah, India. With teaching and research experience of more than 30 years, she is actively engaged in research on oral controlled, modulated, and targeted and topical drug delivery systems, and has received many awards for her work. She has over 270 publications in journals of international and national repute. She also holds three patents and has authored four books and more than 20 book chapters. She has also written many abstracts in various scientific forums and has been a reviewer for national and international journals in pharmaceutics. Professor Pathak has served as a member of the editorial advisory board of AAPS Pharm Sci Tech and is also a member of various professional bodies. She has guided more than 120 PhD and postgraduate students. She is also associated with the Indian pharmaceutical industry in the capacity of a scientific consultant. She is credited as reviewer for several scientific projects, including those of the Knowledge Foundation, Sweden, and Israel Science Foundation. She has participated at national and international seminars and conferences as organizer, invited speaker, and chairperson of scientific sessions. She has been listed in the top 2% Indian scientists in the subsection Pharmacology and Pharmacy, in the World’s Top 2% Scientists list released by Stanford University in 2020–1013. She graduated (Pharmaceutics) from the University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India, earning her doctorate in Pharmacy in 1991 from the same institute. Sudhanshu Mishra, MPharm Faculty of Pharmaceutical Sciences, Mahayogi Gorakhnath University Gorakhpur, Uttar Pradesh, India Sudhanshu Mishra, MPharm, completed his MPharm (Pharmaceutics) from the School of Pharmaceutical Science, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, and is pursuing his PhD from Dr. A.P.J. Abdul Kalam Technical University, Lucknow, Uttar Pradesh, India. He is current working as Assistant Professor in the Faculty of Pharmaceutical Sciences at Mahayogi Gorakhnath University Gorakhpur Uttar Pradesh, India. His areas of interest include novel formulations, nano-herbal formulations, transdermal drug delivery, and localized drug delivery. He has authored over 50 research and review articles for national and international journals. He is currently working on different novel approaches and technologies for targeting chronic diseases. He serves as a reviewer and is also an editorial board member of national and international journals. He participates in academic activities such as international seminars, conferences, workshops, and oral presentations. This book is one of the important contributions to his interest in healthcare and future research areas. Sonali Sundram, MPharm Associate Professor, School of Medical & Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India Sonali Sundram, PhD, is Associate Professor in the School of Medical & Allied Sciences at Galgotias University, Greater Noida, Uttar Pradesh, India. She previously worked as research scientist in a project of ICMR in King George’s Medical University, Lucknow, India. After that, she joined BBDNIIT (Babu Banarasi Das Northern India Institute of Technology), Lucknow. Her PhD (Pharmacy) work was in the area of neurodegeneration and nanoformulation. her area of interest is neurodegeneration, clinical research, and artificial intelligence. She has authored and edited more than 30 books (Wiley, CRC Press/Taylor and Francis, IOP Publishing, Apple Academic Press, Springer Nature, and River Publisher). She has attended and organized more than 15 national and international seminars, conferences, and workshops. She has more than eight patents national and international to her credit. She has published six SCI-indexed manuscripts with reputed international publishers. She has delivered oral presentation in international conferences organized in different European countries. She completed both BPharm and MPharm (Pharmacology) from Dr. A.P.J. Abdul Kalam Technical University, Lucknow, India. |
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