Microbial Biotechnology
Technological Challenges and Developmental Trends

Editors: Bhima Bhukya, PhD
Anjana Devi Tangutur, PhD

Microbial Biotechnology

Published. Now available.
Pub Date: August 2016
Hardback Price: $169.95 US
Hard ISBN: 9781771883320
E-Book ISBN: 9781771883337
Pages: 448pp with index
Binding Type: hardback

The new volume takes an interdisciplinary look at current technical challenges and recent developmental trends in microbial biotechnology. It covers an avalanche of new information available through research by focusing on a broad spectrum of issues on different microorganisms and their recent applications and implications in agriculture, soil science and forestry, industry, and public health and medicine.

Microbes present in our immediate environment have a direct or indirect influence leading to either a harmful or beneficial effect. Microbial Biotechnology: Technological Challenges and Developmental Trends is divided into four major sections that focus on

· Part I: Antimicrobial Agents: Role and Applications in Medicine and Health Care

· Part II: Role of Microorganisms in Agriculture and Plant Biotechnology

· Part III: Microbial Enzymes and Their Potential Industrial Applications

· Part IV: Microorganisms in Environment: Role and Industrial Applications

Topic include organic chemistry, biomass conversion, optimal production processes for different microbes, screening methods, and application of omics approaches such as (meta) genomics, proteomics, and metabolomics, or other biotechnology tools, to provide a deeper understanding of the microbial-based new and emerging products, trends, processes, and technologies.

The chapters present unbiased original research results on microbes by incorporating case studies wherever appropriate.

Providing research findings applicable to the development of new methodologies, applications, and technologies, the book will be a valuable resource for people working in various fields of microbiology.

Part I: Antimicrobial agents: Role and Applications in Medicine and Health Care
1. Antimicrobial Peptides from Plants and Their Applications
B. Bhima and Mohammed Al Saiqali
2. Development of Antitubercular Agents through Hybridization Strategies, Future Challenges, and Perspectives
Srinivas Kantevari, Anvesh Jallapally, Tangutur Anjana Devi, and Dinesh Kumar
3. Novel Bioactive Compounds from an Endophytic Chaetomium arcuatum Strain Saf-2 Isolated from Semecarpus anacardium
C. Ganesh Kumar, Narender Reddy Godumagadda, Poornima Mongolla, Sujitha Pombala, Preethi Badrinarayan, Cheruku Ravindra Reddy, Biswanath Das, K. V. S. Ramakrishna, Balasubramanian Sridhar, and Ahmed Kamal
4. Understanding Role of Biomarkers in Pathogenesis of Sepsis
B. Sandeepta, M. Swathi Raju, A. Nichita, A. Pawan Kumar, and Karthik Rajkumar
5. Role of Copper in Modifying Cisplatin-Induced Cytotoxicity in Yeast
B. Sreedhar and B. Vijaya Lakshmi

Part II: Role of Microorganisms in Agriculture and Plant Biotechnology
6. Role of Microbiome: Insights into the Kin Recognition Process in Oryza sativa by Proteomic and Metabolomic Studies
Tangutur Anjana Devi, Kommalapati Vamsi Krishna, Amrita Dutta Chowdhury, and Neelamraju Sarla
7. Associative Effect of Arbuscular Mycorrhizal Fungi and Rhizobium on Plant Growth and Biological Control of Charcoal Rot in Green Gram [Vigna raidata L. (Wilczek)]
A. Hindumathi, B. N. Reddy, A. Sabitha Rani, and A. Narsimha Reddy
8. Morphological Changes in Vigna radiata Root under Cadmium-Induced Stress in the Presence of Plant Growth Promoting Enterobacter sp. C1D
Rakesh Kumar Sharma, Kavita Barot and G. Archana
9. Potential USe of Trichoderma Species as Promising Plant Growth Stimulator in Tomato (Lycopersicum esculantum L.)
B. N. Reddy, K. Saritha, and A. Hindumathi

Part III: Microbial Enzymes and Their Potential Industrial Applications
10. Strain Improvement of Aspergillus niger for the Enhanced Production of Cellulase in Solid State Fermentation
G. Praveen Kumar Reddy, A. Sridevi, Kanderi Dileep Kumar, G. Ramanjaneyulu, A. Ramya, B. S Shanthi Kumari, and B. Rajasekhar Reddy
11. Screening, Quantification and Purification of Cellulases from Soil Actinomycetes
Payal Das, Renu Solanki, and Monisha Khanna
12. Kinetics Studies of Alkali-Pretreated Sweet Sorghum Bagasse Using Cellulase
L. Saida and K. Venkata Sri Krishna
13. Secretion of Ligninolytic Enzymes by the White Rot Fungus Stereum ostrea Immobilized on Polyurethane Cubes under the Influence of Chlorpyrifos
B. S. Shanthi Kumari, K. Dileep Kumar, K. Y. Usha, A. Ramya, and B. Rajasekhar Reddy
14. Structure and Gas Diffusion Path Analysis of Hydrogenase Enzymes by Homology Modeling
Nivedita Sahu, Anirudh Nelabhotla, and Pradhan Nityananda

Part IV: Microorganisms in Environment: Role and Industrial Applications
15. Saccharomyces cerevisiae as an Efficient Biological Agent for Decolorization of Reactive Dyes in the Textile Industry
B. Bhima, N. Hanumalal, and B. Chandrasekhar
16. Metabolite Profiling and Biological Activities of Extrolites from Aspergillus turcosus Strain KZR131 Isolated from Kaziranga National Park, Assam, India
C. Ganesh Kumar, Poornima Mongolla, Jagadeesh Babu Nanubolu, Pathipati Usha Rani, and Kumar Katragunta
17. Morphological, Cultural and Molecular Diversity of the Salt-Tolerant Alkaliphilic Actinomycetes from Saline Habitats
S. D. Gohel and S. P. Singh
18. Microbial Population Dynamics of Eastern Ghats of Andhra Pradesh for Xylanase Production
G. Ramanjaneyulu, A. Ramya, and B. Rajasekhar Reddy
19. Phylogenetic and Phenogram Based Diversity of Haloalkaliphilic Bacteria from the Saline Desert
Hitarth B. Bhatt and Satya P. Singh
20. Fungal Biotransformation of Drugs: Potential Applications in the Pharma Industry
G.Shyam Prasad and B.Sashidhar Rao

About the Authors / Editors:
Editors: Bhima Bhukya, PhD
Head and Assistant Professor, Department of Microbiology, Osmania University, Hyderabad, India

Bhima Bhukya, PhD, is currently Head and Assistant Professor at the Department of Microbiology, Osmania University, Hyderabad, India, where he has established a probiotics research laboratory.

Dr. Bhima, during his early scientific career, made fundamental contributions in the area of animal probiotics. Subsequently, he contributed towards the development of efficient stress tolerant probiotic yeast and economically viable medium for large-scale production of yeast. His present research interest lies in recombinant probiotics, proteomics and genomics, animal nutrition, biofuels, and bioprocess engineering. He has many years of teaching experience, including several years of undergraduate (veterinary), over ten years of postgraduate (MSc) teaching, and 15 years of research experience. He was awarded the prestigious Raman Post Doctoral fellowship/award in India to study in the USA.

At present he has several PhD research scholars and students working under his supervision. Dr. Bhima published several research articles and book chapters and has presented over 25 papers at various national and international conferences.

He was trained in the area of animal nutrition-gas production technology at ICRISAT, Hyderabad, in the area of proteomics at the University of Hyderabad, Hyderabad and in the area of plant biotechnology at the Center for Plant Molecular Biology, Osmania University, Hyderabad. He is a recipient of many awards for his work, including the HUPO Young Scientist Award by World Human Proteome Organization, the SAB-Young Scientist Award by the Society for Applied Biotechnology, Research Excellence award during Indo global education summit by the Indus Foundation. He has visited countries abroad for scientific interaction and has chaired the scientific sessions during several prestigious national and international conferences.

Dr. Bhima is a life member of AMI, ISCA, BRSI and SAB. He is the Principal Investigator for several ongoing projects. He has made significant contributions to university by working as a warden for PhD scholars hostel and has also been instrumental in several developmental activities at the department and faculty club of Osmania University. As a convener, Dr. Bhima successfully organized a three-day national conference on “Recent Trends in Microbial Biotechnology” and a two-day national seminar on “Advances in Microbial Technology” in 2015 at Osmania University.

Anjana Devi Tangutur, PhD
Scientist, Council of Scientific and Industrial Research-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, India

Anjana Devi Tangutur, PhD, is a Scientist at Council of Scientific and Industrial Research-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, India. Dr. Anjana has over ten years of research experience. She has ,to date, a brilliant academic career, and pursued her doctoral degree at Centre for Cellular & Molecular Biology-CSIR, Hyderabad. Later she joined the Chemical Biology Division of IICT as a Scientist. During her doctoral tenure, she has had significant exposure to various molecular biology and biochemistry approaches and to the mass spectrometry-based proteomics techniques. Dr. Tangutur’s research activities at IICT involve screening of small molecules as anticancer agents (NFk-β, HDAC inhibitors, antitubulin agents, etc.) using various in vitro and in vivo tests. Her research interests lie mainly in applying molecular biology and proteomics based approaches to understand the underlying mechanisms behind disease pathology (in different cancers) or a particular mechanism in a biological system. Her research efforts have been published in reputed international and national journals and conference proceedings. She was selected for AOHUPO/KSMS young scientist award (HUPO 6th Annual World Congress, Seoul, Korea). She has several ongoing projects funded by DBT which include the BioCARe award for women scientists (2013-2016) and also the Rapid grant for young investigator (2013-2016). She served as a subject expert, external examiner and also member of the several interview selection committees in the colleges, university and in the Institute.

She has co-guided several MPharm/MSc students for partial fulfillment of the post graduation degree, and presently several qualified research scholars are pursuing PhD under her guidance. She is also a member of several editorial boards and a reviewer for several journals.

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