Analytical chemistry is the study of what chemicals are present and in what amount in natural and artificial materials. Because these understandings are fundamental in just about every chemical inquiry, analytical chemistry is used to obtain information, ensure safety, and solve problems in many different chemical areas, and is essential in both theoretical and applied chemistry. Analytical chemistry is driven by new and improved instrumentation. This collection presents a broad selection of chapters on analytical chemistry, including methods of determination and analysis as applied to pharmaceuticals, foods, proteins, and more.

CONTENTS: Micelle Enhanced Fluorimetric and Thin Layer Chromatography Densitometric Methods for the Determination of (±) Citalopram and Its S-Enantiomer Escitalopram • A Multidisciplinary Investigation to Determine the Structure and Source of Dimeric Impurities in AMG 517 Drug Substance • Selective Spectrophotometric and Spectrofluorometric Methods for the Determination of Amantadine Hydrochloride in Capsules and Plasma via Derivatization with 1,2-Naphthoquinone-4-sulphonate • Analytical Applications of Reactions of Iron(III) and Hexacyanoferrate(III) with 2,10-Disubstituted Phenothiazines • Quantitative Mass Spectrometric Analysis of Ropivacaine and Bupivacaine in Authentic, Pharmaceutical and Spiked Human Plasma Without Chromatographic Separation • Kinetic Spectrophotometric Determination of Certain Cephalosporins in Pharmaceutical Formulations • Understanding Structural Features of Microbial Lipases—An Overview • Significance Analysis of Microarray for Relative Quantitation of LC /MS Data in Proteomics • Determination of Key Intermediates in Cholesterol and Bile Acid Biosynthesis by Stable Isotope Dilution Mass Spectrometry • A Dynamic Programming Approach for the Alignment of Signal Peaks in Multiple Gas Chromatography-Mass Spectrometry Experiments • Solid-Phase Extraction and Reverse-Phase HPLC :Application to Study the Urinary Excretion Pattern of Benzophenone-3 and Its Metabolite 2,4-Dihydroxybenzophenone in Human Urine • A Simple and Selective Spectrophotometric Method for the Determination of Trace Gold in Real, Environmental, Biological, Geological and Soil Samples Using Bis(Salicylaldehyde) Orthophenylenediamine • more • Index

The science of chemistry is so broad that it is normally broken into fields or branches of specialization. The manufacture of drugs and dyes is one of the most practical industrial applications of chemistry. This collection presents the reader with a broad spectrum of chapters on drugs and dyes, thereby demonstrating key developments in this rapidly changing field. It examines dyes in chemical interaction and production of drugs for pharmaceutical use as well as in forensic work and in the production of materials.

CONTENTS: Solvent Effect on the Spectral Properties of Neutral Red • The Degradation of Organic Dyes by Corona Discharge • UV-Vis Spectrophotometrical and Analytical Methodology for the Determination of Singlet Oxygen in New Antibacterials Drugs • The Application of Resonance Light Scattering Technique for the Determination of Tinidazole in Drugs • Enhanced Trace-Fiber Color Discrimination by Electrospray Ionization Mass Spectrometry:A Quantitative and Qualitative Tool for the Analysis of Dyes Extracted from Sub-millimeter Nylon Fibers • The pKa Distribution of Drugs:Application to Drug Discovery • Determination of μmol-1 Level of Iron (III) in Natural Waters and Total Iron in Drugs by Flow Injection Spectrophotometry • Design and Synthesis of a Noncentrosymmetric Dipyrromethene Dye • The Function of TiO2 with Respect to Sensitizer Stability in Nanocrystalline Dye Solar Cells • Chromatographic and Spectral Analysis of Two Main Extractable Compounds Present in Aqueous Extracts of Laminated Aluminum Foil Used for Protecting LDPE-Filled Drug Vials • The Cold Contact Method as a Simple Drug Interaction Detection System • NMR and Molecular Modelling Studies on the Interaction of Fluconazole with -Cyclodextrin • Spectrophotometric Determination of Etodolac in Pure Form and Pharmaceutical Formulations • Lead Optimization in Discovery Drug Metabolism and Pharmacokinetics:Case Study:The Hepatitis C Virus (HCV) Protease Inhibitor SCH 503034 • Pressure-Tuning Raman Spectra of Diiodine Thioamide Compounds:Models for Antithyroid Drug Activity • Uncertainty Analysis of Drug Concentration in Pharmaceutical Mixtures • Characterization of Thermally Stable Dye-Doped Polyimide Based Electrooptic Materials • Sol-Gel-Derived Silicafilms with Tailored Microstructures for Applications Requiring Organic Dyes • Synthesis and Analysis of Nickel Dithiolene Dyes in a Nematic Liquid Crystal Host • Synthesis of a Photoresponsive Polymer and Its Incorporation into an Organic Superlattice • An Efficient Drug Delivery Vehicle for Botulism Countermeasure • Estimation of Synthetic Accessibility Score of Drug-Like Molecules Based on Molecular Complexity and Fragment Contributions • Rational Mutagenesis to Support Structure-Based Drug Design:MAPKAP Kinase 2 as a Case Study • Nanotechnology Approaches to Crossing the Blood-Brain Barrier and Drug Delivery to the CNS • Index

This collection presents to the reader a broad spectrum of chapters in the various branches of industrial chemistry, which demonstrate key developments in these rapidly changing fields.

CONTENTS: Trace Determination of Linear Alkylbenzene Sulfonates:Application in Artificially Polluted Soil—Carrots System • Are Biogenic Emissions a Significant Source of Summertime Atmospheric Toluene in the Rural Northeastern United States? • Mathematical Modeling of Perfect Decoupled Control System and Its Application:A Reverse Osmosis Desalination Industrial-Scale Unit • Tula Industrial Complex (Mexico) Emissions of SO2 and NO2 During the MCMA 2006 Field Campaign Using a Mobile Mini-DOAS System • Hit from Both Sides:Tracking Industrial and Volcanic Plumes in Mexico City with Surface Measurements and OMI SO2 Retrievals During the MILAGRO Field Campaign • Characterization of a Glucanase Produced by Rhizopus microsporus var. microsporus, and Its Potential for Application in the Brewing Industry • Chemical Analysis and Risk Assessment of Diethyl Phthalate in Alcoholic Beverages with Special Regard to Unrecorded Alcohol • Effects of Photochemical Formation of Mercuric Oxide • more • Index